Melisa was born in Istanbul, She has one brother, She attended two elementary schools and then went to Ata college. She loved ballet and also went to the Alev Baymur school of ballet. She made her stage debut at the age of 14 in a musical Ali Yedi Locali Hurmuz yas. At that time she met with Nilgun Belgun and Levent Ozdilek, and she then appeared in her first TV series, Kadinlar Kulubu. In 2001 she made her movie debut.
In 2005 she presented the 16th Ankara film festival and there she met the director Dervis Zaim who cast her for a part in the movie Cenneti Beklerken. Her list of roles is impressive and has just under forty of them. She was in Magnificent Century as Efsun, also Av Mevsimi. The film in which she starred, Winters Sleep won the Palme d’Or at the 2014 Cannes film festival.
She also does fashion modeling and is a keen advocate for the environment.
She married actor Alican Yucesoy in 2013 but they divorced after only 5 months of marriage. She is currently in a relationship with Harun Tekin.
Very recently she was asked about a project on the screen in France, she confirmed that she is waiting for news.
Melisa is active on Instagram and has 140k followers